Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL307693 | 0.73 | MEN1 (0.38) | KMT2ATSHRKDM4ENPC1ALDH1A1 | |
| SCHEMBL4448887 | 0.72 | HTR6 (0.41) | HTR6MAOACES1MAOBBCHE | |
| SCHEMBL7960264 | 0.72 | HTR6 (0.41) | HTR6MAOACES1MAOBBCHE | |
| SCHEMBL30041622 | 0.70 | HTR6 (0.48) | HTR6MAOACES1MAOBTSHR | |
| SCHEMBL4448883 | 0.70 | HTR6 (0.40) | HTR6MAOACES1MAOBBCHE | |
| SCHEMBL30057710 | 0.70 | HTR6 (0.40) | HTR6MAOACES1MAOBBCHE | |
| SCHEMBL17073935 | 0.70 | HTR6 (0.40) | HTR6MAOACES1MAOBBCHE | |
| SCHEMBL6925588 | 0.70 | HTR6 (0.48) | HTR6MAOACES1MAOBTSHR | |
| SCHEMBL21694409 | 0.70 | HTR6 (0.40) | HTR6MAOACES1MAOBBCHE | |
| SCHEMBL12743937 | 0.70 | HTR6 (0.44) | HTR6MAOACES1MAOBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105899216-B | Pyrrolo [1,2-f ] [1,2,4] triazines useful for the treatment of respiratory syncytial virus infection | 吉利德科学公司 | 2019-03-05 | — | — | CN | claimed |
| CN-103923070-A | Efficient Process For The Preparation Of Lapatinib And Salts Thereof By Means Of New Intermediates | ITALIANA SINT SPA | 2014-07-16 | — | — | CN | claimed |
| US-8093354-B2 | Process for preparing glycopeptide phosphonate derivatives | THERAVANCE, INC. (US) | 2012-01-10 | — | — | US | claimed |
| US-20110060122-A1 | PROCESS FOR PREPARING GLYCOPEPTIDE PHOSPHONATE DERIVATIVES | THERAVANCE, INC. (US) | 2011-03-10 | — | — | US | claimed |
| US-20080227963-A1 | Process for preparing glycopeptide phosphonate derivatives | CUMBERLAND PHARMACEUTICALS INC. | 2008-09-18 | — | — | US | claimed |
| EP-1418933-B1 | PROCESS FOR PREPARING GLYCOPEPTIDE PHOSPHONATE DERIVATIVES | THERAVANCE INC (US) | 2007-05-02 | — | — | EP | claimed |
| EP-1419174-B1 | PROCESS FOR PREPARING GLYCOPEPTIDE DERIVATIVES | THERAVANCE INC (US) | 2007-04-18 | — | — | EP | claimed |
| US-20060264607-A1 | Process for preparing glycopeptide phosphonate derivatives | CUMBERLAND PHARMACEUTICALS INC. | 2006-11-23 | — | — | US | claimed |
| CN-1246036-C | Process for preparing glycopeptide phosphonate derivatives | THERAVANCE INC (US) | 2006-03-22 | — | — | CN | claimed |
| US-7015305-B2 | Process for preparing glycopeptide derivatives | THERAVANCE, INC. (US) | 2006-03-21 | — | — | US | claimed |
| EP-1419174-A4 | PROCESS FOR PREPARING GLYCOPEPTIDE DERIVATIVES | THERAVANCE INC (US) | 2005-10-12 | — | — | EP | claimed |
| CN-1610692-A | Process for preparing glycopeptide derivatives | THERAVANCE INC (US) | 2005-04-27 | — | — | CN | claimed |
| CN-1547481-A | Process for preparing glycopeptide phosphonate derivatives | ������ҩ������˾ | 2004-11-17 | — | — | CN | claimed |
| EP-1418933-A4 | PROCESS FOR PREPARING GLYCOPEPTIDE PHOSPHONATE DERIVATIVES | THERAVANCE INC (US) | 2004-10-27 | — | — | EP | claimed |
| EP-1418933-A2 | PROCESS FOR PREPARING GLYCOPEPTIDE PHOSPHONATE DERIVATIVES | Theravance, Inc. (US) | 2004-05-19 | — | — | EP | claimed |
| EP-1419174-A2 | PROCESS FOR PREPARING GLYCOPEPTIDE DERIVATIVES | Theravance, Inc. (US) | 2004-05-19 | — | — | EP | claimed |
| WO-2003029270-A2 | PROCESS FOR PREPARING GLYCOPEPTIDE PHOSPHONATE DERIVATIVES | THERAVANCE, INC. (US) | 2003-04-10 | — | — | WO | claimed |
| US-20030069391-A1 | Process for preparing glycopeptide phosphonate derivatives | CUMBERLAND PHARMACEUTICALS INC. | 2003-04-10 | — | — | US | claimed |
| US-20030045457-A1 | Process for preparing glycopeptide derivatives | CUMBERLAND PHARMACEUTICALS INC. | 2003-03-06 | — | — | US | claimed |
| WO-2003018607-A2 | PROCESS FOR PREPARING GLYCOPEPTIDE DERIVATIVES | THERAVANCE, INC. (US) | 2003-03-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045457-A1 | Process for preparing glycopeptide derivatives | GYPA, VIP, OGT | HTR6 4005/4885MAOA 3292/4885CES1 3689/4885 |
| US-20060264607-A1 | Process for preparing glycopeptide phosphonate derivatives | PGLS, GYPA, PAG1 | HTR6 4402/4885MAOA 4574/4885CES1 3054/4885 |
| US-20080227963-A1 | Process for preparing glycopeptide phosphonate derivatives | PGLS, GYPA, PAG1 | HTR6 4402/4885MAOA 4574/4885CES1 3054/4885 |
| US-20110060122-A1 | PROCESS FOR PREPARING GLYCOPEPTIDE PHOSPHONATE DERIVATIVES | PGLS, GYPA, PAG1 | HTR6 4402/4885MAOA 4574/4885CES1 3054/4885 |
| US-20030069391-A1 | Process for preparing glycopeptide phosphonate derivatives | PGLS, GYPA, PAG1 | HTR6 4402/4885MAOA 4574/4885CES1 3054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.