SCHEMBL307693

SCHEMBL307693

[CH2]C1=CCc2cc3ccccc3cc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
TP53 P04637 3/20 0.35
HSD17B10 Q99714 3/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
TSHR P16473 2/20 0.35
MAPK1 P28482 2/20 0.35
CASP1 P29466 2/20 0.35
CASP7 P55210 2/20 0.35
HIF1A Q16665 1/20 0.35
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
PKM P14618 1/20 0.31
CYP2C19 P33261 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL308272 0.73 HTR6 (0.40) KMT2AALDH1A1HPGDTSHRKDM4E
SCHEMBL7155040 0.71 MEN1 (0.34) MEN1KMT2ATP53HSD17B10ALDH1A1
Hydrochloric Acid SCHEMBL8159133 0.70 MEN1 (0.31) MEN1KMT2A
Hydrochloric Acid SCHEMBL6554714 0.70 MEN1 (0.31) MEN1KMT2A
SCHEMBL787473 0.69 MEN1 (0.37) MEN1KMT2ATP53HSD17B10ALDH1A1
SCHEMBL7931392 0.68 MEN1 (0.35) MEN1KMT2ATP53HSD17B10ALDH1A1
SCHEMBL1655232 0.67 MEN1 (0.46) MEN1KMT2ATP53HSD17B10ALDH1A1
SCHEMBL30924248 0.67 MEN1 (0.46) MEN1KMT2ATP53HSD17B10ALDH1A1
SCHEMBL5917329 0.67 MEN1 (0.35) MEN1KMT2AMAPTGAA
SCHEMBL4859806 0.67 MEN1 (0.38) MEN1KMT2ATP53HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3068405-B1 PYRROLO [1,2,F][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS GILEAD SCIENCES INC (US) 2019-05-01 EP claimed
EP-2646411-B1 PREPARATION OF PET PRECURSOR BLUE EARTH DIAGNOSTICS LTD (GB) 2017-08-16 EP claimed
US-9493469-B2 Piperidine inhibitors of Janus kinase 3 AUSPEX PHARMACEUTICALS, INC. (US) 2016-11-15 US claimed
US-8093354-B2 Process for preparing glycopeptide phosphonate derivatives THERAVANCE, INC. (US) 2012-01-10 US claimed
US-20110060122-A1 PROCESS FOR PREPARING GLYCOPEPTIDE PHOSPHONATE DERIVATIVES THERAVANCE, INC. (US) 2011-03-10 US claimed
US-20080227963-A1 Process for preparing glycopeptide phosphonate derivatives CUMBERLAND PHARMACEUTICALS INC. 2008-09-18 US claimed
EP-1418933-B1 PROCESS FOR PREPARING GLYCOPEPTIDE PHOSPHONATE DERIVATIVES THERAVANCE INC (US) 2007-05-02 EP claimed
EP-1419174-B1 PROCESS FOR PREPARING GLYCOPEPTIDE DERIVATIVES THERAVANCE INC (US) 2007-04-18 EP claimed
US-20060264607-A1 Process for preparing glycopeptide phosphonate derivatives CUMBERLAND PHARMACEUTICALS INC. 2006-11-23 US claimed
US-7015305-B2 Process for preparing glycopeptide derivatives THERAVANCE, INC. (US) 2006-03-21 US claimed
US-6979723-B2 Process for preparing glycopeptide phosphonate derivatives THERAVANCE, INC. (US) 2005-12-27 US claimed
US-20030069391-A1 Process for preparing glycopeptide phosphonate derivatives CUMBERLAND PHARMACEUTICALS INC. 2003-04-10 US claimed
US-20030045457-A1 Process for preparing glycopeptide derivatives CUMBERLAND PHARMACEUTICALS INC. 2003-03-06 US claimed
US-11999757-B2 Synthesis of boronate ester derivatives and uses thereof MELINTA SUBSIDIARY CORP. (US) 2024-06-04 US disclosed
CN-117986153-A Ionizable cationic lipid compound, and preparation method and application thereof 晟迪生物医药(苏州)有限公司 2024-05-07 CN disclosed
CN-114085243-B Pyrrolo [1,2-f ] [1,2,4] triazines useful for the treatment of respiratory syncytial virus infection 吉利德科学公司 2024-04-26 CN disclosed
EP-1289999-B1 ANTITUMORAL ANALOGS OF ET-743 PHARMA MAR SA (ES) 2004-11-17 EP disclosed
US-20030119021-A1 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions CAPROTEC BIOANALYTICS GMBH (DE) 2003-06-26 US disclosed
US-20030069391-A1 Process for preparing glycopeptide phosphonate derivatives CUMBERLAND PHARMACEUTICALS INC. 2003-04-10 US disclosed
US-20030045457-A1 Process for preparing glycopeptide derivatives CUMBERLAND PHARMACEUTICALS INC. 2003-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030045457-A1 Process for preparing glycopeptide derivatives GYPA, VIP, OGT MEN1 3165/4885KMT2A 4121/4885TP53 3209/4885
US-20060264607-A1 Process for preparing glycopeptide phosphonate derivatives PGLS, GYPA, PAG1 MEN1 2435/4885KMT2A 4252/4885TP53 1881/4885
US-20080227963-A1 Process for preparing glycopeptide phosphonate derivatives PGLS, GYPA, PAG1 MEN1 2435/4885KMT2A 4252/4885TP53 1881/4885
US-20110060122-A1 PROCESS FOR PREPARING GLYCOPEPTIDE PHOSPHONATE DERIVATIVES PGLS, GYPA, PAG1 MEN1 2435/4885KMT2A 4252/4885TP53 1881/4885
US-11999757-B2 Synthesis of boronate ester derivatives and uses thereof ADH5, ADH1A, ADH7 MEN1 3249/4885KMT2A 3000/4885TP53 4688/4885
US-20030069391-A1 Process for preparing glycopeptide phosphonate derivatives PGLS, GYPA, PAG1 MEN1 2435/4885KMT2A 4252/4885TP53 1881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.