Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GSK3A | P49840 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.41 |
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.41 |
| ▸ | XPO1 | O14980 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23780336 | 0.85 | PIN1 (0.50) | MEN1KMT2AMAP2K4HAO2MAPT | |
| SCHEMBL30829475 | 0.75 | AKT2 (0.62) | MEN1KMT2AHAO2MAPTSMN1; SMN2 | |
| SCHEMBL20213984 | 0.75 | AKT2 (0.62) | MEN1KMT2AHAO2MAPTSMN1; SMN2 | |
| SCHEMBL10875241 | 0.74 | HSP90AA1 (0.54) | LMNAGSK3AGSK3BRPS6KB1CSNK1D | |
| SCHEMBL6955300 | 0.73 | SMN1; SMN2 (0.52) | LMNAALDH1A1GSK3AGSK3BRPS6KB1 | |
| SCHEMBL2016547 | 0.72 | SMN1; SMN2 (0.45) | LMNAALDH1A1GSK3AGSK3BRPS6KB1 | |
| SCHEMBL269910 | 0.71 | KDM4E (0.51) | ALDH1A1GSK3AGSK3BRPS6KB1CSNK1D | |
| SCHEMBL6302515 | 0.71 | KMT2A (0.43) | ALDH1A1GSK3BMEN1KMT2AGAA | |
| SCHEMBL5317799 | 0.70 | TRPM8 (0.49) | LMNAALDH1A1MEN1KMT2ATRPM8 | |
| SCHEMBL11351745 | 0.70 | ALDH1A1 (0.58) | LMNAALDH1A1MEN1KMT2ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118930533-A | Substituted pyrazole compounds and methods of using the same for treating hyperproliferative diseases | 班塔姆制药有限责任公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-110603254-B | Substituted pyrazole compounds and methods of using the same for treating hyperproliferative diseases | 班塔姆制药有限责任公司 | 2024-04-12 | — | — | CN | disclosed |