SCHEMBL30833000

SCHEMBL30833000

CCOCCOc1cc(C)c(-c2ccccc2)c(C)c1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 14/20 0.55
PPARG P37231 2/20 0.43
PPARA Q07869 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.41
PPARD Q03181 1/20 0.41
NCF1 P14598 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30832999 0.85 FFAR1 (0.45) FFAR1PPARGPPARA
SCHEMBL30833001 0.85 FFAR1 (0.49) FFAR1PPARGPPARAPPARDMEN1
SCHEMBL30833003 0.84 FFAR1 (0.49) FFAR1PPARGPPARA
SCHEMBL28008147 0.84 FFAR1 (0.53) FFAR1
SCHEMBL30833002 0.83 FFAR1 (0.50) FFAR1PPARGPPARAPPARD
SCHEMBL1099545 0.82 FFAR1 (0.62) FFAR1
SCHEMBL1099011 0.81 FFAR1 (0.53) FFAR1
SCHEMBL10682048 0.79 KCNA3 (0.44) FFAR1PPARGPPARAPPARD
SCHEMBL28008148 0.78 FFAR1 (0.40) FFAR1L3MBTL1NCF1MEN1KMT2A
SCHEMBL4061901 0.78 CHRNB2 (0.57) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11905230-B2 Phenoxyacetic acid derivatives, preparation method thereof and use thereof as medicament CHINA PHARMACEUTICAL UNIVERSITY (CN) 2024-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11905230-B2 Phenoxyacetic acid derivatives, preparation method thereof and use thereof as medicament SLC5A1, PYGL, GPR119 FFAR1 57/4885PPARG 39/4885PPARA 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.