Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833000 | 0.84 | FFAR1 (0.55) | FFAR1 | |
| SCHEMBL1099545 | 0.81 | FFAR1 (0.62) | FFAR1 | |
| SCHEMBL5038332 | 0.80 | MAPK1 (0.62) | APPMAPK1ALOX15TSHR | |
| SCHEMBL1099011 | 0.80 | FFAR1 (0.53) | FFAR1BRD4 | |
| SCHEMBL27913199 | 0.77 | FFAR1 (0.59) | FFAR1 | |
| SCHEMBL1133232 | 0.75 | ACHE (0.55) | BRD4TSHRDYRK1ACLK4 | |
| SCHEMBL11896604 | 0.75 | ACHE (0.54) | BRD4DYRK1ACLK4 | |
| SCHEMBL12578512 | 0.75 | FFAR1 (0.71) | FFAR1 | |
| SCHEMBL15219217 | 0.73 | KDM4E (0.57) | MAPK1TSHR | |
| SCHEMBL15295214 | 0.73 | ALDH1A1 (0.48) | APPMAPK1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710381-A | Novel 3-hydroxy-5-arylisothiazole derivative | MOCHIDA PHARM CO LTD | 2015-06-17 | — | — | CN | disclosed |
| CN-102712610-B | Novel 3-hydroxy-5-arylisothiazole derivatives | MOCHIDA PHARM CO LTD | 2015-03-04 | — | — | CN | disclosed |