Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | CCNC | P24863 | 3/20 | 0.40 |
| ▸ | CDK8 | P49336 | 3/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 3/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833122 | 0.75 | MAPT (0.47) | — | |
| SCHEMBL31536999 | 0.68 | HTR3E (0.56) | HRH4CHRNB2CHRNA4NCF1HTR3A | |
| SCHEMBL24312145 | 0.67 | MAPT (0.45) | NCF1 | |
| SCHEMBL4420245 | 0.66 | ADRB1 (0.53) | NCF1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL19145912 | 0.65 | MAPT (0.42) | NCF1 | |
| SCHEMBL30366123 | 0.65 | TLR9 (0.40) | FAAHHTR1AHTR6HTR2C | |
| SCHEMBL26088142 | 0.65 | MAPT (0.42) | — | |
| SCHEMBL1736748 | 0.64 | CHRNB2 (0.53) | HRH4CHRNB2CHRNA4ADRB2CHRNA1 | |
| SCHEMBL5466686 | 0.63 | CHRNB2 (0.51) | HRH4CHRNB2CHRNA4ADRB2CHRNA1 | |
| SCHEMBL24312437 | 0.63 | RAF1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587432-A1 | M4 ACTIVATORS/MODULATORS AND USES THEREOF | Cerevel Therapeutics, LLC (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059249-A1 | M4 ACTIVATORS/MODULATORS AND USES THEREOF | CEREVEL THERAPEUTICS, LLC (US) | 2024-03-21 | — | — | WO | disclosed |