Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 4/20 | 0.54 |
| ▸ | ARG2 | P78540 | 4/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30201437 | 1.00 | ARG1 (0.54) | ARG1ARG2LTA4HDRD2DRD4 | |
| Trifluoroacetic Acid SCHEMBL30201583 | 0.90 | LTA4H (0.48) | ARG1ARG2LTA4HDRD2DRD4 | |
| Trifluoroacetic Acid SCHEMBL30201771 | 0.88 | LTA4H (0.53) | ARG1ARG2LTA4HMAPTMAPK1 | |
| SCHEMBL30833195 | 0.86 | DRD2 (0.48) | ARG1ARG2LTA4HDRD2DRD4 | |
| SCHEMBL3881487 | 0.86 | DRD2 (0.48) | ARG1ARG2LTA4HDRD2DRD4 | |
| SCHEMBL3881484 | 0.86 | DRD2 (0.48) | ARG1ARG2LTA4HDRD2DRD4 | |
| Trifluoroacetic Acid SCHEMBL30201435 | 0.86 | LTA4H (0.49) | ARG1ARG2LTA4HMEN1KMT2A | |
| SCHEMBL10815249 | 0.80 | CXCR6 (0.46) | ARG1ARG2LTA4HDRD2DRD4 | |
| Trifluoroacetic Acid SCHEMBL30201381 | 0.79 | KCNH2 (0.53) | ARG1ARG2POLBKCNH2OPRK1 | |
| Trifluoroacetic Acid SCHEMBL1920595 | 0.78 | ARG1 (0.52) | ARG1ARG2DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009330-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2023-02-02 | — | — | WO | disclosed |