Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 3/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30201532 | 0.87 | DPP4 (0.41) | OPRK1KCNH2OPRM1DPP4VNN1 | |
| SCHEMBL20070534 | 0.75 | VNN1 (0.41) | OPRK1GABRA1GABRA5VNN1OPRL1 | |
| SCHEMBL1022931 | 0.72 | KDM4E (0.39) | DPP4 | |
| SCHEMBL20148639 | 0.72 | VNN1 (0.37) | OPRM1GABRA1GABRA5VNN1OPRL1 | |
| SCHEMBL30833237 | 0.69 | OPRM1 (0.31) | OPRK1KCNH2OPRM1 | |
| SCHEMBL30833221 | 0.68 | PTPN11 (0.40) | — | |
| SCHEMBL17289014 | 0.66 | TNKS (0.46) | GABRA1GABRA5 | |
| SCHEMBL30833230 | 0.66 | JAK2 (0.41) | OPRK1KCNH2OPRM1 | |
| SCHEMBL15021133 | 0.65 | CHRM2 (0.58) | OPRK1KCNH2OPRM1 | |
| SCHEMBL21772974 | 0.65 | CHRM2 (0.58) | OPRK1KCNH2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729914-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2024-03-19 | — | — | CN | disclosed |