Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833200 | 0.87 | OPRK1 (0.37) | DPP4KCNH2OPRK1OPRM1VNN1 | |
| Trifluoroacetic Acid SCHEMBL30201424 | 0.83 | OPRM1 (0.52) | DPP4DPP8DPP7DPP9KCNH2 | |
| Trifluoroacetic Acid SCHEMBL30201381 | 0.80 | KCNH2 (0.53) | KCNH2OPRK1OPRM1KDM4EF2 | |
| Trifluoroacetic Acid SCHEMBL30201435 | 0.79 | LTA4H (0.49) | KCNH2OPRK1OPRM1KDM4EF2 | |
| Trifluoroacetic Acid SCHEMBL30201373 | 0.76 | ARG1 (0.38) | KCNH2OPRK1OPRM1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL30201500 | 0.76 | CYP3A4 (0.39) | DPP4DPP7CYP2D6HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL31622406 | 0.75 | ARG1 (0.37) | KCNH2OPRK1OPRM1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL30201522 | 0.75 | ARG1 (0.37) | KCNH2OPRK1OPRM1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL30201490 | 0.74 | ARG1 (0.35) | KCNH2OPRK1OPRM1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL30201583 | 0.73 | LTA4H (0.48) | DPP4KCNH2OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009330-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2023-02-02 | — | — | WO | disclosed |