Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 14/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 13/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833213 | 0.89 | OPRK1 (0.48) | OPRM1OPRD1LTA4HOPRK1KCNH2 | |
| SCHEMBL30833198 | 0.88 | OPRK1 (0.47) | OPRM1OPRD1LTA4HOPRK1KCNH2 | |
| SCHEMBL30833209 | 0.87 | OPRK1 (0.56) | OPRM1OPRD1LTA4HOPRK1KCNH2 | |
| SCHEMBL30833216 | 0.87 | KCNH2 (0.58) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL30833235 | 0.80 | PARP1 (0.41) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL30833238 | 0.80 | OPRK1 (0.59) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL30833220 | 0.79 | OPRM1 (0.58) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL30344212 | 0.77 | HTR1A (0.46) | OPRM1OPRD1OPRK1 | |
| SCHEMBL30833224 | 0.77 | OPRK1 (0.59) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL30833229 | 0.77 | OPRK1 (0.39) | OPRM1OPRD1OPRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729914-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2024-03-19 | — | — | CN | disclosed |