Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR1F | P30939 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30344212 | 0.84 | HTR1A (0.46) | ROCK2PIM1PIM3OPRK1OPRM1 | |
| SCHEMBL30833216 | 0.83 | KCNH2 (0.58) | OPRK1KCNH2OPRM1OPRD1 | |
| SCHEMBL30833224 | 0.77 | OPRK1 (0.59) | OPRK1KCNH2OPRM1OPRD1 | |
| SCHEMBL30833198 | 0.76 | OPRK1 (0.47) | OPRK1KCNH2OPRM1OPRD1 | |
| SCHEMBL30833220 | 0.76 | OPRM1 (0.58) | OPRK1KCNH2OPRM1OPRD1 | |
| SCHEMBL3962847 | 0.75 | JAK2 (0.44) | ROCK2PIM1PIM3SCDHTR1A | |
| SCHEMBL30833209 | 0.75 | OPRK1 (0.56) | OPRK1KCNH2OPRM1OPRD1 | |
| SCHEMBL30833213 | 0.75 | OPRK1 (0.48) | OPRK1KCNH2OPRM1OPRD1HTR1A | |
| SCHEMBL30833238 | 0.74 | OPRK1 (0.59) | OPRK1KCNH2OPRM1OPRD1 | |
| SCHEMBL29820574 | 0.74 | HTR1A (0.41) | ROCK2PIM1PIM3FGFR1SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729914-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2024-03-19 | — | — | CN | disclosed |