Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | JUN | P05412 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.30 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | CDC25A | P30304 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21663004 | 0.80 | SMN1; SMN2 (0.34) | TRIM24SMN1; SMN2OPRK1PDE4DPIN1 | |
| SCHEMBL31125012 | 0.72 | CYP11B2 (0.38) | SMN1; SMN2PIN1CYP11B1CYP11B2TYRO3 | |
| SCHEMBL30833288 | 0.72 | TRIM24 (0.36) | TRIM24BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL29769797 | 0.72 | CD38 (0.35) | — | |
| SCHEMBL6844626 | 0.71 | STK4 (0.49) | SMN1; SMN2PIN1CYP11B1CYP11B2TYRO3 | |
| SCHEMBL30833279 | 0.71 | OPRK1 (0.35) | TRIM24OPRK1PDE4DCYP11B1CYP11B2 | |
| SCHEMBL18168138 | 0.70 | SMN1; SMN2 (0.44) | TRIM24SMN1; SMN2TYRO3DYRK1BBMPR1B | |
| SCHEMBL21831489 | 0.69 | TRIM24 (0.40) | TRIM24OPRK1PDE4DBMPR1BBMPR1A | |
| SCHEMBL29769801 | 0.69 | TRIM24 (0.40) | TRIM24OPRK1PDE4DBMPR1BBMPR1A | |
| SCHEMBL29764153 | 0.69 | TRIM24 (0.40) | TRIM24OPRK1PDE4DBMPR1BBMPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580829-A | Quinoline and azaquinolines as inhibitors of CD38 | 勃林格英格翰国际有限公司 | 2024-02-20 | — | — | CN | disclosed |