Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | WNT3 | P56703 | 2/20 | 0.39 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE8B | O95263 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833385 | 0.88 | POLB (0.45) | GPR119POLBWNT3SFRP1KDM4E | |
| SCHEMBL30833512 | 0.82 | WNT3 (0.36) | GPR119POLBWNT3SFRP1KDM4E | |
| SCHEMBL30833463 | 0.81 | MEN1 (0.43) | GPR119WNT3SFRP1NR1H2NR1H3 | |
| SCHEMBL17942411 | 0.81 | GPR119 (0.52) | GPR119POLB | |
| SCHEMBL29529620 | 0.81 | GPR119 (0.52) | GPR119POLB | |
| SCHEMBL30833487 | 0.80 | SFRP1 (0.40) | GPR119POLBWNT3SFRP1KDM4E | |
| SCHEMBL30833425 | 0.78 | RIPK1 (0.45) | GPR119POLBWNT3SFRP1NR1H2 | |
| SCHEMBL28527698 | 0.74 | POLB (0.44) | GPR119POLBKDM4EUCHL1MEN1 | |
| SCHEMBL30833508 | 0.73 | WNT3 (0.36) | WNT3SFRP1NR1H2NR1H3MEN1 | |
| SCHEMBL17942533 | 0.73 | SFRP1 (0.38) | GPR119SFRP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |