Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833663 | 1.00 | PIN1 (0.36) | PIN1MAPTYTHDC1EGFRKMT2A | |
| SCHEMBL30833627 | 0.88 | BCL6 (0.39) | PIN1MAPTIGF1R | |
| SCHEMBL30833628 | 0.85 | IGF1R (0.46) | PIN1MAPTKMT2AMEN1IGF1R | |
| SCHEMBL30833745 | 0.85 | AURKA (0.43) | KMT2AIGF1RCDK1PTK2 | |
| SCHEMBL30833754 | 0.85 | MAPT (0.36) | PIN1MAPTYTHDC1EGFRKMT2A | |
| SCHEMBL30833638 | 0.82 | PTK2 (0.45) | YTHDC1IGF1RCDK1PTK2 | |
| SCHEMBL30833793 | 0.81 | MAPT (0.34) | PIN1MAPTYTHDC1KMT2AMEN1 | |
| SCHEMBL30833733 | 0.78 | PIN1 (0.36) | PIN1MAPTYTHDC1KMT2AMEN1 | |
| SCHEMBL22807434 | 0.73 | EGFR (0.42) | PIN1MAPTEGFRKMT2AMEN1 | |
| SCHEMBL29549370 | 0.73 | EGFR (0.42) | PIN1MAPTEGFRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |