Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.33 |
| ▸ | CDK2 | P24941 | 3/20 | 0.33 |
| ▸ | CCNK | O75909 | 2/20 | 0.33 |
| ▸ | CCND3 | P30281 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CLIC1 | O00299 | 1/20 | 0.32 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833627 | 0.88 | BCL6 (0.39) | MAPTIGF1RAURKAPIN1LRRK2 | |
| SCHEMBL30833745 | 0.85 | AURKA (0.43) | IGF1RAURKAKMT2ACDK2CDK1 | |
| SCHEMBL30833645 | 0.85 | PIN1 (0.36) | MAPTIGF1RGAAYTHDC1PIN1 | |
| SCHEMBL30833628 | 0.85 | IGF1R (0.46) | MAPTIGF1RPIN1KMT2AMEN1 | |
| SCHEMBL30833663 | 0.85 | PIN1 (0.36) | MAPTIGF1RGAAYTHDC1PIN1 | |
| SCHEMBL30833793 | 0.83 | MAPT (0.34) | MAPTGAAYTHDC1PIN1KMT2A | |
| SCHEMBL30833638 | 0.82 | PTK2 (0.45) | IGF1RYTHDC1CDK2CDK9PTGS2 | |
| SCHEMBL30833765 | 0.78 | PKMYT1 (0.38) | MAPTIGF1RGAAAURKAYTHDC1 | |
| SCHEMBL15946706 | 0.77 | LRRK2 (0.52) | AURKALRRK2CCNA2CDK2CCNK | |
| SCHEMBL21600781 | 0.76 | KMT2A (0.52) | MAPTIGF1RAURKAKMT2ALRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |