Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.44 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4025891 | 1.00 | IGF1R (0.52) | IGF1RKMT2AMEN1ALKCDK19 | |
| SCHEMBL24073506 | 0.85 | CCNA2 (0.44) | KMT2AALKALDH1A1MAPTALOX15 | |
| SCHEMBL30223473 | 0.85 | CCNA2 (0.44) | KMT2AALKALDH1A1MAPTALOX15 | |
| SCHEMBL25056502 | 0.84 | IGF1R (0.51) | IGF1RKMT2AMEN1ALKCDK19 | |
| SCHEMBL25056242 | 0.81 | IGF1R (0.48) | IGF1RKMT2AMEN1ALKCDK19 | |
| SCHEMBL24716006 | 0.80 | ULK1 (0.48) | IGF1RLRRK2PTK2 | |
| SCHEMBL17544687 | 0.79 | IGF1R (0.55) | IGF1RKMT2AMEN1ALKCDK19 | |
| SCHEMBL24260666 | 0.79 | IGF1R (0.55) | IGF1RKMT2AMEN1ALKCDK19 | |
| SCHEMBL30833802 | 0.79 | IGF1R (0.55) | IGF1RKMT2AMEN1ALKCDK19 | |
| SCHEMBL15699963 | 0.79 | L3MBTL1 (0.48) | KMT2AMEN1ALDH1A1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |