Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.47 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.45 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 4/20 | 0.44 |
| ▸ | CDK9 | P50750 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833714 | 0.85 | ALK (0.46) | SYKCDK2CDK9EGFRCDC7 | |
| SCHEMBL29190658 | 0.83 | ALK (0.59) | EGFRALKMETFLT3 | |
| SCHEMBL31251206 | 0.81 | EGFR (0.63) | EGFRALK | |
| SCHEMBL30833700 | 0.81 | KDR (0.52) | SYKCDK2CDK9EGFRDAPK3 | |
| SCHEMBL30833740 | 0.81 | PTK2 (0.50) | SYKCDK2CDK9CDC7JAK2 | |
| SCHEMBL16966032 | 0.79 | INSR (0.53) | MAP3K7CDK2CDK9EGFRCCNA2 | |
| SCHEMBL30833711 | 0.79 | CDK2 (0.42) | SYKMAP3K7CDK2CDK9EGFR | |
| SCHEMBL30833669 | 0.78 | ALK (0.46) | SYKCDK2CDK9ULK1CCNA2 | |
| SCHEMBL30833661 | 0.78 | ALK (0.46) | CDK2CDK9ULK1CCNA2CCNK | |
| SCHEMBL16966003 | 0.78 | MET (0.46) | MAP3K7CDK2CDK9EGFRCCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |