Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 14/20 | 0.46 |
| ▸ | SYK | P43405 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | CCNK | O75909 | 2/20 | 0.42 |
| ▸ | CDK9 | P50750 | 2/20 | 0.42 |
| ▸ | ULK1 | O75385 | 1/20 | 0.42 |
| ▸ | CCND3 | P30281 | 1/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833661 | 0.85 | ALK (0.46) | ALKFLT3CCNA2CDK2CCNK | |
| SCHEMBL30833776 | 0.85 | ALK (0.48) | ALKSYKFLT3MET | |
| SCHEMBL30833785 | 0.84 | ALK (0.51) | ALKFLT3ULK1 | |
| SCHEMBL30833687 | 0.84 | ALK (0.50) | ALKFLT3METULK1 | |
| SCHEMBL29190563 | 0.83 | ALK (0.64) | ALKSYKFLT3MET | |
| SCHEMBL30833790 | 0.83 | IGF1R (0.44) | ALK | |
| SCHEMBL30833656 | 0.81 | ALK (0.48) | ALKFLT3 | |
| SCHEMBL30833700 | 0.81 | KDR (0.52) | ALKSYKFLT3METCDK2 | |
| SCHEMBL30833797 | 0.80 | ALK (0.44) | ALKFLT3 | |
| SCHEMBL30833783 | 0.78 | SYK (0.47) | ALKSYKFLT3METCCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |