Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30834251 | 0.80 | MAPT (0.45) | LMNAKMT2AALDH1A1KDM4EGAA | |
| SCHEMBL30643716 | 0.77 | HRH2 (0.47) | LMNASMN1; SMN2POLBL3MBTL1PTGDR2 | |
| SCHEMBL31358402 | 0.75 | HTR2A (0.41) | LMNASMN1; SMN2L3MBTL1TDP1TSHR | |
| SCHEMBL31357912 | 0.74 | PTGDR2 (0.41) | LMNASMN1; SMN2POLBPTGDR2HRH2 | |
| SCHEMBL27563812 | 0.73 | LMNA (0.48) | LMNASMN1; SMN2POLBBCHEKMT2A | |
| SCHEMBL9627031 | 0.72 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2POLBBCHETDP1 | |
| SCHEMBL7740552 | 0.72 | SMN1; SMN2 (0.47) | LMNASMN1; SMN2POLBBCHEL3MBTL1 | |
| SCHEMBL31341987 | 0.71 | P2RY12 (0.34) | LMNASMN1; SMN2POLBHRH2HRH1 | |
| SCHEMBL30058722 | 0.71 | POLB (0.39) | LMNASMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL16299538 | 0.71 | ALDH1A1 (0.43) | LMNASMN1; SMN2POLBL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073502-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | ACCUTAR BIOTECHNOLOGY INC. (US) | 2024-04-04 | — | — | WO | disclosed |