SCHEMBL3083486

SCHEMBL3083486

COc1ccc(-c2nc(-c3ccccc3Cl)n(-n3ccnc3)c2-c2ccccc2Cl)cc1OC

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
TP53 P04637 2/20 0.45
NPC1 O15118 1/20 0.45
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
PDE4A P27815 2/20 0.42
QPCT Q16769 2/20 0.41
TEK Q02763 1/20 0.37
PDE10A Q9Y233 1/20 0.37
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
PIK3CD O00329 1/20 0.36
GRM7 Q14831 1/20 0.36
ACACA Q13085 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28767208 0.87 ALDH1A1 (0.54) L3MBTL1MEN1KMT2ATP53NPC1
SCHEMBL29732925 0.82 L3MBTL1 (0.53) L3MBTL1MEN1KMT2ATP53NPC1
SCHEMBL7897274 0.82 L3MBTL1 (0.53) L3MBTL1MEN1KMT2ATP53NPC1
SCHEMBL3072033 0.82 LMNA (0.42) TP53ALDH1A1SMN1; SMN2PDE4ATEK
SCHEMBL7044209 0.78 NPC1 (0.54) L3MBTL1MEN1KMT2ATP53NPC1
SCHEMBL62627 0.76 L3MBTL1 (0.50) L3MBTL1MEN1KMT2ATP53NPC1
SCHEMBL29373643 0.76 L3MBTL1 (0.50) L3MBTL1MEN1KMT2ATP53NPC1
SCHEMBL22507470 0.73 L3MBTL1 (0.50) L3MBTL1MEN1KMT2ATP53NPC1
SCHEMBL22710269 0.70 L3MBTL1 (0.43) L3MBTL1MEN1KMT2ATP53NPC1
SCHEMBL29895743 0.70 L3MBTL1 (0.43) L3MBTL1MEN1KMT2ATP53NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1292861-B1 MULTIDIRECTIONAL PHOTOREACTIVE ABSORPTION METHOD 3M INNOVATIVE PROPERTIES CO (US) 2014-11-19 EP disclosed
EP-1295180-B1 PROCESS FOR PRODUCING MICROFLUIDIC ARTICLES 3M INNOVATIVE PROPERTIES CO (US) 2013-05-22 EP disclosed
EP-1546809-B1 MULTIPHOTON PHOTOSENSITIZATION SYSTEM 3M INNOVATIVE PROPERTIES CO (US) 2010-12-15 EP disclosed
US-7790353-B2 Multidirectional photoreactive absorption method 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-09-07 US disclosed
US-7790347-B2 Multi-photon reacted articles with inorganic particles and method for fabricating structures 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-09-07 US disclosed
EP-1303791-B1 MULTICOLOR IMAGING USING MULTIPHOTON PHOTOCHEMICAL PROCESSES 3M INNOVATIVE PROPERTIES CO (US) 2009-08-19 EP disclosed
EP-1292862-B1 MULTIPASS MULTIPHOTON ABSORPTION METHOD AND APPARATUS 3M INNOVATIVE PROPERTIES CO (US) 2009-08-19 EP disclosed
EP-1297021-B1 MULTIPHOTON PHOTOSENSITIZATION SYSTEM 3M INNOVATIVE PROPERTIES CO (US) 2009-03-18 EP disclosed
US-20090035528-A1 Multi-photon reacted articles with inorganic particles and method for fabricating structures 3M INNOVATIVE PROPERTIES COMPANY 2009-02-05 US disclosed
US-7381516-B2 Multiphoton photosensitization system 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-06-03 US disclosed
EP-1295180-A2 PROCESS FOR PRODUCING MICROFLUIDIC ARTICLES 3M Innovative Properties Company (US) 2003-03-26 EP disclosed
EP-1292862-A2 MULTIPASS MULTIPHOTON ABSORPTION METHOD AND APPARATUS 3M Innovative Properties Company (US) 2003-03-19 EP disclosed
EP-1292861-A2 MULTIDIRECTIONAL PHOTOREACTIVE ABSORPTION METHOD 3M Innovative Properties Company (US) 2003-03-19 EP disclosed
EP-1292863-A2 MULTIPHOTON ABSORPTION METHOD USING PATTERNED LIGHT 3M Innovative Properties Company (US) 2003-03-19 EP disclosed
WO-2001096962-A2 MULTIPHOTON ABSORPTION METHOD USING PATTERNED LIGHT 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-12-20 WO disclosed
WO-2001096958-A2 PROCESS FOR PRODUCING MICROFLUIDIC ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-12-20 WO disclosed
WO-2001096959-A2 MULTIDIRECTIONAL PHOTOREACTIVE ABSORPTION METHOD 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-12-20 WO disclosed
WO-2001096961-A2 MULTIPASS MULTIPHOTON ABSORPTION METHOD AND APPARATUS 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-12-20 WO disclosed
WO-2001096409-A2 MULTIPHOTON PHOTOSENSITIZATION SYSTEM 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-12-20 WO disclosed
WO-2001096452-A2 METHOD FOR MAKING OR ADDING STRUCTURES TO AN ARTICLE 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-12-20 WO disclosed