Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30832013 | 0.89 | DRD2 (0.49) | KCNH2HTR1ADRD2CACNA1IHTR2A | |
| SCHEMBL30840016 | 0.85 | HTR2A (0.51) | KCNH2DRD2CACNA1IHTR2AHTR2C | |
| SCHEMBL8222029 | 0.80 | CKS1B (0.53) | DRD2 | |
| SCHEMBL7137625 | 0.77 | ALDH1A1 (0.57) | KMT2AMEN1DRD2HTR2AHTR2C | |
| SCHEMBL28037376 | 0.76 | DRD2 (0.50) | KCNH2KMT2ADRD2CACNA1I | |
| SCHEMBL4274668 | 0.76 | KCNH2 (0.56) | KCNH2DRD2CACNA1I | |
| SCHEMBL24833934 | 0.76 | SIGMAR1 (0.57) | DRD2HTR2ASIGMAR1 | |
| SCHEMBL13965728 | 0.75 | CACNA1I (0.56) | KCNH2DRD2CACNA1I | |
| SCHEMBL7804764 | 0.75 | DRD2 (0.49) | KCNH2KMT2ADRD2CACNA1I | |
| SCHEMBL1970814 | 0.75 | MEN1 (0.48) | KCNH2KMT2AMEN1DRD2CACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024067302-A1 | AMIDE COMPOUND AND USE THEREOF IN PREPARATION OF INHIBITOR OF SIGMA2 AND 5HT2A | 瀚远医药有限公司 | 2024-04-04 | — | — | WO | disclosed |