Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31613824 | 0.99 | POLB (0.40) | POLBTP53LMNAMAPTTHRB | |
| SCHEMBL31613842 | 0.96 | OPRM1 (0.39) | POLBTP53LMNAMAPTTHRB | |
| SCHEMBL31546219 | 0.81 | TP53 (0.41) | POLBTP53LMNAMAPTKMT2A | |
| SCHEMBL30842135 | 0.81 | POLB (0.46) | POLBTP53LMNAMAPTTHRB | |
| SCHEMBL30842143 | 0.79 | OPRM1 (0.40) | LMNAKMT2AOPRM1OPRD1OGFRL1 | |
| SCHEMBL30842165 | 0.79 | TP53 (0.47) | POLBTP53LMNAMAPTKDM4E | |
| SCHEMBL31613833 | 0.75 | RXFP1 (0.36) | POLBLMNAOPRM1OPRD1OGFRL1 | |
| SCHEMBL31047350 | 0.69 | TSHR (0.37) | LMNAMAPTKMT2AOPRM1OPRD1 | |
| SCHEMBL31047351 | 0.69 | TSHR (0.37) | LMNAMAPTKMT2AOPRM1OPRD1 | |
| SCHEMBL31047343 | 0.69 | OPRM1 (0.43) | POLBTP53LMNAOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4567032-A1 | KIF18A INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR AND USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024051755-A1 | KIF18A INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR AND USE THEREOF | 长春金赛药业有限责任公司 | 2024-03-14 | — | — | WO | disclosed |