Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FSHR | P23945 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | IDH2 | P48735 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31047350 | 1.00 | TSHR (0.37) | TSHRFSHRAKT1AKT2AKT3 | |
| SCHEMBL31047340 | 0.85 | IDH1 (0.37) | TSHRFSHROPRM1OPRD1OGFRL1 | |
| SCHEMBL31047342 | 0.85 | IDH1 (0.37) | TSHRFSHROPRM1OPRD1OGFRL1 | |
| SCHEMBL31613833 | 0.77 | RXFP1 (0.36) | TSHRFSHROPRM1OPRD1OGFRL1 | |
| SCHEMBL31047339 | 0.75 | KIF18A (0.51) | — | |
| SCHEMBL31047343 | 0.75 | OPRM1 (0.43) | OPRM1OPRD1OGFRL1IDH1RXFP1 | |
| SCHEMBL27362170 | 0.73 | GSK3B (0.37) | TSHRFSHROPRM1OPRD1OGFRL1 | |
| SCHEMBL31613842 | 0.71 | OPRM1 (0.39) | OPRM1OPRD1OGFRL1RXFP1MAPT | |
| SCHEMBL30842139 | 0.71 | TGFBR1 (0.49) | OPRM1OPRD1OGFRL1RXFP1KMT2A | |
| SCHEMBL31047346 | 0.71 | OPRM1 (0.41) | OPRM1OPRD1OGFRL1IDH1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149189-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-07-18 | — | — | WO | disclosed |