Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FSHR | P23945 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31047350 | 0.77 | TSHR (0.37) | RXFP1BRD4P2RX7BRD9OPRM1 | |
| SCHEMBL31047351 | 0.77 | TSHR (0.37) | RXFP1BRD4P2RX7BRD9OPRM1 | |
| SCHEMBL31613842 | 0.77 | OPRM1 (0.39) | RXFP1BRD4P2RX7BRD9OPRM1 | |
| SCHEMBL31613824 | 0.76 | POLB (0.40) | BRD4BRD9OPRM1OPRD1OGFRL1 | |
| SCHEMBL30842140 | 0.75 | POLB (0.42) | OPRM1OPRD1OGFRL1LMNAPOLB | |
| SCHEMBL30842143 | 0.74 | OPRM1 (0.40) | RXFP1BRD4P2RX7BRD9OPRM1 | |
| SCHEMBL31047343 | 0.72 | OPRM1 (0.43) | RXFP1BRD4BRD9OPRM1OPRD1 | |
| SCHEMBL30842149 | 0.71 | KIF18A (0.49) | — | |
| SCHEMBL31037927 | 0.69 | GRM2 (0.33) | — | |
| SCHEMBL31037911 | 0.69 | PIK3CB (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4567032-A1 | KIF18A INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR AND USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |