SCHEMBL3084239

SCHEMBL3084239

[CH2]Cc1ccc(C)cc1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.38
IDO1 P14902 1/20 0.35
KMT2A Q03164 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
MAPT P10636 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
RAB9A P51151 1/20 0.35
ATM Q13315 1/20 0.35
CYP1A2 P05177 3/20 0.35
CYP2A6 P11509 2/20 0.35
CYP2C9 P11712 2/20 0.34
MAPK1 P28482 2/20 0.34
CYP2C19 P33261 2/20 0.34
CYP3A4 P08684 1/20 0.34
LMNA P02545 1/20 0.34
GABRA1 P14867 2/20 0.34
GABRG2 P18507 2/20 0.34
GABRB3 P28472 2/20 0.34
GABRB2 P47870 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10822907 0.83 HPGD (0.36) HPGDIDO1KMT2ANPSR1MAPT
SCHEMBL2355598 0.81 TAAR1 (0.40) HPGDIDO1KMT2ANPSR1MAPT
SCHEMBL13932525 0.81 AMY1A (0.42) HPGDIDO1KMT2ANPSR1MAPT
SCHEMBL29393025 0.79 KMT2A (0.48) HPGDIDO1KMT2ANPSR1MAPT
SCHEMBL8230054 0.79 GRIN2D (0.41) HPGDIDO1KMT2ANPSR1MAPT
SCHEMBL7039692 0.79 KMT2A (0.48) HPGDIDO1KMT2ANPSR1MAPT
SCHEMBL20083513 0.77 MAPT (0.38) HPGDIDO1KMT2ANPSR1MAPT
SCHEMBL12345506 0.77 IDO1 (0.35) HPGDIDO1KMT2ANPSR1MAPT
SCHEMBL5974477 0.77 IDO1 (0.61) HPGDIDO1KMT2ANPSR1MAPT
SCHEMBL21995434 0.77 PYCR1 (0.46) HPGDIDO1KMT2ARAB9ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024132895-A1 MICROBIOCIDAL DIHYDROOXADIAZINYL PYRIDAZINONE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-06-27 WO disclosed
WO-2024132901-A1 MICROBIOCIDAL PYRIDAZINE DIHYDROOXADIAZINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-27 WO disclosed
US-9686990-B2 Spiroindolinepiperidine derivatives SYNGENTA PARTICIPATIONS AG (CH) 2017-06-27 US disclosed
US-20160007608-A1 SPIROINDOLINEPIPERIDINE DERIVATIVES SYNGENTA LIMITED (GB) 2016-01-14 US disclosed
US-20100234220-A1 Oxooxetanes as Fungicidal Agents BAYER CROPSCIENCE AG (DE) 2010-09-16 US disclosed
US-5466821-A Triazole ring containing fungicides, intermediates ZENECA LIMITED (GB) 1995-11-14 US disclosed
US-5395942-A Fungicides for plants ZENECA LIMITED (GB) 1995-03-07 US disclosed
US-5354729-A Controlling weeds at low dosage; nonphytotoxic SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-11 US disclosed
EP-0579469-A2 N-acyldihydroquinoline derivatives as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-01-19 EP disclosed
US-5004494-A Fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234220-A1 Oxooxetanes as Fungicidal Agents CYP51A1, PNPO, AOX1 HPGD 1013/4885IDO1 171/4885KMT2A 3109/4885
US-20160007608-A1 SPIROINDOLINEPIPERIDINE DERIVATIVES RECQL, OPRD1, SKP1 HPGD 1299/4885IDO1 2427/4885KMT2A 2827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.