Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169084 | 1.00 | TRPV4 (0.52) | TRPV4KIF11KDM4EGAACA2 | |
| Hydrochloric Acid SCHEMBL29970288 | 0.98 | TRPV4 (0.50) | TRPV4KIF11KDM4EGAACA2 | |
| SCHEMBL244098 | 0.79 | TRPV4 (0.52) | TRPV4KCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL3701877 | 0.79 | KDM4E (0.57) | TRPV4KDM4EKCNH2MAP4K4PIK3CA | |
| SCHEMBL5077871 | 0.79 | TRPV4 (0.52) | TRPV4KDM4EKCNH2MAP4K4PIK3CA | |
| SCHEMBL18379351 | 0.79 | CA2 (0.50) | CA2CA4CA12CA9CA1 | |
| SCHEMBL29948975 | 0.79 | TRPV4 (0.52) | TRPV4KCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL18231250 | 0.79 | KCNH2 (0.55) | TRPV4KCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL5077872 | 0.78 | KDM4E (0.55) | TRPV4KDM4EKCNH2MAP4K4PIK3CA | |
| Hydrochloric Acid SCHEMBL27930121 | 0.78 | KDM4E (0.55) | TRPV4KDM4EKCNH2MAP4K4PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558481-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024020156-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-25 | — | — | WO | disclosed |