Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 11/20 | 0.36 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.35 |
| ▸ | RXRG | P48443 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30847777 | 0.84 | CMA1 (0.40) | CACNA1HCMA1 | |
| SCHEMBL30847625 | 0.80 | POLQ (0.54) | CMA1MGAT2 | |
| SCHEMBL30847592 | 0.79 | CMA1 (0.34) | CACNA1HCMA1MGAT2 | |
| SCHEMBL30847650 | 0.71 | ALOX5 (0.39) | RXRARXRBRXRGMGAT2 | |
| SCHEMBL30847719 | 0.71 | TACR1 (0.38) | CMA1 | |
| SCHEMBL29315902 | 0.68 | RXRA (0.44) | GPR17PTGDR2RXRARXRBRXRG | |
| SCHEMBL40666 | 0.68 | ADRB1 (0.51) | CMA1 | |
| SCHEMBL13735640 | 0.66 | SCN9A (0.46) | CMA1 | |
| SCHEMBL20768063 | 0.65 | CETP (0.42) | — | |
| SCHEMBL7392895 | 0.64 | HCAR1 (0.46) | CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598901-A1 | PYRROLIDINE AND IMIDAZOLIDINE BASED DNA POLYMERASE THETA INHIBITORS AND USE THEREOF | Thomas Jefferson University (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076964-A1 | PYRROLIDINE AND IMIDAZOLIDINE BASED DNA POLYMERASE THETA INHIBITORS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-04-11 | — | — | WO | disclosed |