Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3082339 | 0.84 | LMNA (0.47) | LMNAHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL27174936 | 0.80 | HSD17B10 (0.46) | LMNAHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL27174954 | 0.78 | LMNA (0.42) | LMNAHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL1502786 | 0.77 | HSD17B10 (0.46) | LMNAHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL20954074 | 0.77 | HDAC6 (0.39) | LMNAHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL3073391 | 0.75 | ALDH1A1 (0.52) | LMNAHPGDALDH1A1MAPTMAPK1 | |
| SCHEMBL27174924 | 0.75 | FFAR1 (0.60) | LMNAHPGDALDH1A1MAPTCDK2 | |
| SCHEMBL3087197 | 0.73 | ALDH1A1 (0.50) | LMNAHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL11751962 | 0.73 | LMNA (0.56) | LMNAHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL13143669 | 0.71 | KMT2A (0.37) | LMNAHPGDHSD17B10ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110092783-B | Preparation method of thiamethoxam | 湖南化工研究院有限公司 | 2020-11-20 | — | — | CN | disclosed |
| US-7795442-B2 | Preparation of thiazoles | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-14 | — | — | US | disclosed |
| US-20090198054-A1 | PREPARATION OF THIAZOLES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-08-06 | — | — | US | disclosed |
| US-7538229-B2 | Preparation of thiazoles | SYNGENTA CROP PROTECTION, INC. (US) | 2009-05-26 | — | — | US | disclosed |
| US-20080076920-A1 | PREPARATION OF THIAZOLES | SYNGENTA CROP PROTECTION, INC. (US) | 2008-03-27 | — | — | US | disclosed |
| US-7323564-B2 | Preparation of thiazoles | SYNGENTA CROP PROTECTION, INC. (US) | 2008-01-29 | — | — | US | disclosed |
| US-20070055063-A1 | PREPARATION OF THIAZOLES | SYNGENTA CROP PROTECTION, INC. (US) | 2007-03-08 | — | — | US | disclosed |
| US-7161011-B2 | Reactin a thiazole compound with glycidyl aldehyde | SYNGENTA CROP PROTECTION, INC. (US) | 2007-01-09 | — | — | US | disclosed |
| EP-0873326-B1 | PROCESS FOR PREPARING 2-CHLOROTHIAZOLE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2005-11-09 | — | — | EP | disclosed |
| EP-0946531-B1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-11-02 | — | — | EP | disclosed |
| US-6211381-B1 | CHEMICAL INTERMEDIATES | NOVARTIS CROP PROTECTION, INC. | 2001-04-03 | — | — | US | disclosed |
| US-6121455-A | CHLORINATION, SALT FORMATION | NOVARTIS CROP PROTECTION, INC. (US) | 2000-09-19 | — | — | US | disclosed |
| EP-0958286-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | Novartis AG (CH) | 1999-11-24 | — | — | EP | disclosed |
| EP-0946531-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | Novartis AG (CH) | 1999-10-06 | — | — | EP | disclosed |
| EP-0946532-A1 | PREPARATION OF THIAZOLES | Novartis AG (CH) | 1999-10-06 | — | — | EP | disclosed |
| EP-0873326-A1 | PROCESS FOR PREPARING 2-CHLOROTHIAZOLE COMPOUNDS | Novartis AG (CH) | 1998-10-28 | — | — | EP | disclosed |
| WO-1998032747-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | NOVARTIS AG (CH) | 1998-07-30 | — | — | WO | disclosed |
| WO-1998027074-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | NOVARTIS AG (CH) | 1998-06-25 | — | — | WO | disclosed |
| WO-1998027075-A1 | PREPARATION OF THIAZOLES | NOVARTIS AG (CH) | 1998-06-25 | — | — | WO | disclosed |
| WO-1997020829-A1 | PROCESS FOR PREPARING 2-CHLOROTHIAZOLE COMPOUNDS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076920-A1 | PREPARATION OF THIAZOLES | OXSR1, OSR1, OSBPL3 | LMNA 4017/4885HPGD 4868/4885HSD17B10 3139/4885 |
| US-20070055063-A1 | PREPARATION OF THIAZOLES | SLC5A1, TST, TCOF1 | LMNA 723/4885HPGD 4827/4885HSD17B10 2290/4885 |
| US-20090198054-A1 | PREPARATION OF THIAZOLES | OXSR1, OSR1, OSBPL3 | LMNA 4017/4885HPGD 4868/4885HSD17B10 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.