Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CLK3 | P49761 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27237622 | 0.90 | DYRK1A (0.43) | F2RL3DYRK1AALDH1A1TDP1PTGES | |
| SCHEMBL30848965 | 0.83 | LMNA (0.38) | F2RL3ALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL24989587 | 0.81 | IMPDH2 (0.36) | F2RL3DYRK1ACLK1CLK2CLK3 | |
| SCHEMBL30224768 | 0.81 | LMNA (0.36) | F2RL3ALDH1A1NQO2MTNR1AMTNR1B | |
| SCHEMBL30182949 | 0.81 | DYRK1A (0.44) | DYRK1AALDH1A1TDP1CLK1CLK2 | |
| SCHEMBL30848953 | 0.77 | F2RL3 (0.41) | F2RL3ALDH1A1MEN1KMT2APIM1 | |
| SCHEMBL27237592 | 0.77 | F2RL3 (0.41) | F2RL3ALDH1A1MEN1KMT2APIM1 | |
| SCHEMBL30224943 | 0.77 | F2RL3 (0.40) | F2RL3ALDH1A1MEN1KMT2APIM1 | |
| SCHEMBL24988935 | 0.74 | LMNA (0.35) | F2RL3ALDH1A1PTGESMEN1MAPK1 | |
| SCHEMBL30224804 | 0.73 | ADORA2A (0.33) | CLK1CLK2CLK3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794917-A | Novel indole derivatives, pharmaceutical compositions containing the same and uses thereof | 水疗免疫疗法有限公司 | 2024-03-29 | — | — | CN | disclosed |