Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | FBP1 | P09467 | 3/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CD38 | P28907 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30224768 | 0.88 | LMNA (0.36) | LMNANQO2MTNR1AMTNR1BKDM4E | |
| SCHEMBL30849019 | 0.83 | F2RL3 (0.42) | LMNANQO2MTNR1AMTNR1BF2RL3 | |
| SCHEMBL30848970 | 0.78 | REN (0.31) | — | |
| SCHEMBL24988935 | 0.78 | LMNA (0.35) | LMNAF2RL3ALDH1A1MAPTMAPK1 | |
| SCHEMBL8848629 | 0.72 | XDH (0.45) | KDM4EALDH1A1MAPTMAPK1HPGD | |
| SCHEMBL27237622 | 0.71 | DYRK1A (0.43) | NQO2MTNR1AMTNR1BF2RL3ALDH1A1 | |
| SCHEMBL30848953 | 0.70 | F2RL3 (0.41) | KDM4EF2RL3ALDH1A1MAPTFBP1 | |
| SCHEMBL27237592 | 0.70 | F2RL3 (0.41) | KDM4EF2RL3ALDH1A1MAPTFBP1 | |
| SCHEMBL30224926 | 0.69 | KIT (0.37) | CD38 | |
| SCHEMBL30224960 | 0.69 | ALDH1A1 (0.33) | LMNAKDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794917-A | Novel indole derivatives, pharmaceutical compositions containing the same and uses thereof | 水疗免疫疗法有限公司 | 2024-03-29 | — | — | CN | disclosed |