Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30854977 | 0.87 | ROCK2 (0.49) | ALDH1A1KDM4EHPGDL3MBTL1GAA | |
| SCHEMBL26545860 | 0.83 | HIF1A (0.47) | ALDH1A1KDM4EHPGDL3MBTL1GAA | |
| SCHEMBL15011086 | 0.82 | SMN1; SMN2 (0.66) | ALDH1A1KDM4EHPGDL3MBTL1GAA | |
| SCHEMBL2446060 | 0.81 | KMT2A (0.52) | ALDH1A1KDM4EHPGDGAASMN1; SMN2 | |
| SCHEMBL13210757 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDL3MBTL1GAA | |
| SCHEMBL16646057 | 0.81 | ALOX12 (0.69) | ALDH1A1L3MBTL1GAAMAPTPKM | |
| Hydrochloric Acid SCHEMBL2378252 | 0.80 | KMT2A (0.52) | ALDH1A1KDM4EHPGDGAASMN1; SMN2 | |
| SCHEMBL3635025 | 0.77 | KDM4E (0.60) | KDM4EHPGDL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL16257097 | 0.77 | RAB9A (0.65) | ALDH1A1KDM4EHPGDGAASMN1; SMN2 | |
| SCHEMBL322837 | 0.77 | GAA (0.60) | ALDH1A1KDM4EHPGDL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | claimed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |