Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29194774 | 1.00 | MTNR1A (0.47) | MTNR1AMTNR1BTSPOCTSLCTSB | |
| SCHEMBL7472970 | 0.84 | CTSS (0.62) | CTSLCTSBCTSSALDH1A1PTGES | |
| SCHEMBL1295318 | 0.82 | ALDH1A1 (0.47) | MTNR1AMTNR1BGFERHSD17B10L3MBTL1 | |
| SCHEMBL3418637 | 0.82 | ALDH1A1 (0.62) | GFERHSD17B10L3MBTL1ALDH1A1HTT | |
| SCHEMBL17336383 | 0.81 | MTNR1A (0.48) | MTNR1AMTNR1BHSD17B2GFERHSD17B10 | |
| SCHEMBL1295923 | 0.81 | MTNR1A (0.50) | MTNR1AMTNR1BGFERHSD17B10L3MBTL1 | |
| SCHEMBL11358431 | 0.80 | CTSB (0.47) | TSPOCTSLCTSBCTSSALDH1A1 | |
| SCHEMBL15647155 | 0.80 | ALDH1A1 (0.49) | MTNR1AMTNR1BGFERHSD17B10L3MBTL1 | |
| SCHEMBL6204579 | 0.80 | MTNR1A (0.58) | MTNR1AMTNR1BALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL24097453 | 0.79 | MTNR1B (0.51) | MTNR1AMTNR1BALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |