Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438530 | 1.00 | HTR2A (0.32) | HTR2AHTR2CKCNH2P2RX3P2RX2 | |
| SCHEMBL29272808 | 0.87 | ADRB2 (0.33) | ADRB2ADRB1 | |
| SCHEMBL15242458 | 0.86 | P2RX3 (0.43) | HTR2CP2RX3P2RX2HIF1AADRB2 | |
| SCHEMBL3249451 | 0.85 | P2RX7 (0.34) | HIF1AADRB2ADRB1CYP2D6NFKB1 | |
| SCHEMBL18805724 | 0.84 | P2RX7 (0.34) | P2RX3P2RX2 | |
| SCHEMBL16113094 | 0.84 | P2RX3 (0.32) | P2RX3P2RX2 | |
| SCHEMBL29272814 | 0.84 | HIF1A (0.33) | HTR2CHIF1AADRB2ADRB1BLM | |
| SCHEMBL30777910 | 0.84 | HIF1A (0.33) | HTR2CHIF1AADRB2ADRB1BLM | |
| SCHEMBL1742873 | 0.82 | TRPA1 (0.34) | HIF1AADRB2ADRB1CYP2D6NFKB1 | |
| SCHEMBL16629528 | 0.81 | APLNR (0.34) | HTR2AKCNH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667236-B | 1, 5-Dihydro-2, 4-benzodiazepine-3-one derivative and application thereof | 江苏恩华药业股份有限公司 | 2024-04-26 | — | — | CN | disclosed |