Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 2/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2481608 | 0.78 | RAB9A (0.52) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL17678354 | 0.77 | CYP11B2 (0.58) | CDK9CCNT1MAPTALDH1A1L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL29063683 | 0.77 | RAB9A (0.51) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL17678202 | 0.75 | CDK9 (0.51) | CDK9CCNT1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL30847394 | 0.75 | CDK9 (0.51) | CDK9CCNT1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL30856700 | 0.75 | KDM4E (0.65) | CDK9CCNT1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL7261471 | 0.74 | CYP1A2 (0.56) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL3969164 | 0.74 | MEN1 (0.50) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL3964662 | 0.73 | MEN1 (0.53) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL21025787 | 0.72 | CYP11B2 (0.49) | CDK9CCNT1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917405-A | KIF18A protein inhibitors | 杭州邦顺制药有限公司 | 2024-04-23 | — | — | CN | disclosed |