Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | VEGFA | P15692 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | RHEB | Q15382 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16556058 | 1.00 | EPAS1 (0.63) | EPAS1MEN1MAPTKMT2AVEGFA | |
| SCHEMBL1997338 | 0.83 | TLR4 (0.46) | EPAS1MEN1MAPTKMT2ACETP | |
| SCHEMBL5089480 | 0.83 | EPAS1 (0.47) | EPAS1MEN1MAPTKMT2AVEGFA | |
| SCHEMBL22069596 | 0.79 | HSPB1 (0.56) | EPAS1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL14662124 | 0.78 | SLC6A4 (0.54) | EPAS1MEN1MAPTKMT2ARHEB | |
| SCHEMBL14744331 | 0.78 | MEN1 (0.61) | EPAS1MEN1MAPTKMT2ARHEB | |
| SCHEMBL16555467 | 0.78 | EPAS1 (1.00) | EPAS1MEN1MAPTKMT2AVEGFA | |
| SCHEMBL30856914 | 0.78 | EPAS1 (1.00) | EPAS1MEN1MAPTKMT2AVEGFA | |
| SCHEMBL28317228 | 0.76 | ALDH1A1 (0.53) | EPAS1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL13306553 | 0.75 | MEN1 (0.41) | EPAS1MEN1MAPTKMT2ACETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49948-E1 | Aryl ethers and uses thereof | PELOTON THERAPEUTICS, INC. (US) | 2024-04-30 | — | — | US | disclosed |