Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.72 |
| ▸ | ST14 | Q9Y5Y6 | 6/20 | 0.72 |
| ▸ | PLAU | P00749 | 1/20 | 0.72 |
| ▸ | F10 | P00742 | 5/20 | 0.63 |
| ▸ | FURIN | P09958 | 1/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.59 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.55 |
| ▸ | F12 | P00748 | 1/20 | 0.54 |
| ▸ | F7 | P08709 | 1/20 | 0.54 |
| ▸ | F3 | P13726 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | WDR5 | P61964 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3085721 | 0.85 | F2 (0.83) | F2ST14PLAUF10FURIN | |
| SCHEMBL483100 | 0.84 | ST14 (1.00) | F2ST14PLAUF10FURIN | |
| SCHEMBL17084494 | 0.84 | ST14 (1.00) | F2ST14PLAUF10FURIN | |
| SCHEMBL11498069 | 0.79 | PARP10 (0.77) | ALDH1A1MAPK1HTTL3MBTL1BLM | |
| SCHEMBL13270794 | 0.79 | ST14 (0.79) | F2ST14PLAUF10FURIN | |
| SCHEMBL6579180 | 0.78 | F2 (1.00) | F2ST14PLAUF10FURIN | |
| SCHEMBL19286912 | 0.77 | ST14 (0.83) | F2ST14PLAUF10FURIN | |
| SCHEMBL20364177 | 0.75 | ST14 (0.79) | F2ST14PLAUF10FURIN | |
| SCHEMBL6580920 | 0.75 | F10 (1.00) | F2ST14PLAUF10FURIN | |
| SCHEMBL14556365 | 0.74 | F2 (0.59) | F2ST14PLAUF10FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070088067-A1 | Novel amidine compounds for treating microbial infections | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2007-04-19 | — | — | US | disclosed |
| US-20070088067-A1 | Novel amidine compounds for treating microbial infections | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088067-A1 | Novel amidine compounds for treating microbial infections | ARG1, ARG2, GSDMD | F2 4291/4885ST14 3956/4885PLAU 2303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.