Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22325047 | 1.00 | BCL2L1 (0.34) | BCL2L1SLC6A3SLC6A2ACHEBCL2 | |
| SCHEMBL31759009 | 0.83 | PTGS2 (0.35) | BCL2L1SLC6A3BCL2 | |
| SCHEMBL22325249 | 0.83 | SLC6A3 (0.50) | SLC6A3SLC6A2ACHEBCL2 | |
| SCHEMBL30834660 | 0.79 | SLC6A3 (0.41) | SLC6A3SLC6A2ACHE | |
| SCHEMBL33529723 | 0.79 | BCL2L1 (0.40) | BCL2L1SLC6A3SLC6A2ACHEBCL2 | |
| SCHEMBL22325185 | 0.79 | BCL2L1 (0.40) | BCL2L1SLC6A3SLC6A2ACHEBCL2 | |
| SCHEMBL30857697 | 0.77 | BCL2L1 (0.69) | BCL2L1BCL2 | |
| SCHEMBL22325101 | 0.75 | BCL2L1 (0.56) | BCL2L1BCL2 | |
| SCHEMBL30857610 | 0.75 | BCL2L1 (0.56) | BCL2L1BCL2 | |
| SCHEMBL1113744 | 0.74 | BCL2L1 (0.52) | BCL2L1SLC6A3SLC6A2ACHEBCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024067818-A1 | CHIMERIC COMPOUND USED FOR TARGETED DEGRADATION OF BCL-2 PROTEIN, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 江苏恒瑞医药股份有限公司 | 2024-04-04 | — | — | WO | disclosed |