SCHEMBL308616

SCHEMBL308616

O=C1OC(=O)c2cc(C(c3cccc4c3C(=O)OC4=O)(C(F)(F)F)C(F)(F)F)ccc21

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 2/20 0.33
TYMS P04818 2/20 0.32
NPC1 O15118 1/20 0.31
PLA2G1B P04054 1/20 0.31
NFKB1 P19838 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ATG4B Q9Y4P1 1/20 0.31
PTPN5 P54829 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL544762 0.85 ALOX15 (0.41) ALOX15TDP1TYMS
SCHEMBL20477107 0.83 ALOX15 (0.34) ALOX15TDP1ALDH1A1TYMS
SCHEMBL49774 0.83 ALOX15 (0.43) ALOX15TDP1ALDH1A1TYMSNPC1
SCHEMBL12476543 0.79 NPC1 (0.39) ALOX15TDP1ALDH1A1TYMSNPC1
SCHEMBL15914778 0.79 ALOX15 (0.39) ALOX15TDP1ALDH1A1NPC1PLA2G1B
SCHEMBL17119191 0.77 ALOX15 (0.40) ALOX15TDP1ALDH1A1TYMSNPC1
SCHEMBL24595895 0.75 NOTUM (0.37) ALOX15TDP1ALDH1A1NPC1PLA2G1B
SCHEMBL26015925 0.75 ALDH1A1 (0.36) ALOX15TDP1ALDH1A1NPC1PLA2G1B
SCHEMBL14537633 0.75 ALDH1A1 (0.36) ALOX15TDP1ALDH1A1NPC1PLA2G1B
SCHEMBL15033891 0.75 ALDH1A1 (0.36) ALOX15TDP1ALDH1A1NPC1PLA2G1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11566108-B2 Polyimide film, laminate and surface material for display DAI NIPPON PRINTING CO., LTD. (JP) 2023-01-31 US claimed
US-10059682-B1 Asymmetric dianhyrdrides and methods of making the same THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2018-08-28 US claimed
US-7381849-B1 Synthesis of asymmetric tetracarboxylic acids and dianhydrides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2008-06-03 US claimed
US-11566108-B2 Polyimide film, laminate and surface material for display DAI NIPPON PRINTING CO., LTD. (JP) 2023-01-31 US disclosed
US-10935700-B2 Optical film and image display device DAI NIPPON PRINTING CO., LTD. (JP) 2021-03-02 US disclosed
WO-2020255864-A1 POLYIMIDE FILM, POLYIMIDE VARNISH, METHOD FOR PRODUCING POLYIMIDE FILM, MULTILAYER BODY, MEMBER FOR DISPLAYS, TOUCH PANEL MEMBER, LIQUID CRYSTAL DISPLAY DEVICE AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE 大日本印刷株式会社 2020-12-24 WO disclosed
US-20200386917-A1 OPTICAL FILM AND IMAGE DISPLAY DEVICE DAI NIPPON PRINTING CO., LTD. (JP) 2020-12-10 US disclosed
US-10792901-B2 Optical film and image display device DAI NIPPON PRINTING CO., LTD. (JP) 2020-10-06 US disclosed
US-20190315105-A1 OPTICAL FILM AND IMAGE DISPLAY DEVICE DAI NIPPON PRINTING CO., LTD. (JP) 2019-10-17 US disclosed
WO-2019078051-A1 POLYIMIDE FILM, POLYIMIDE FILM PRODUCTION METHOD, LAMINATE, SURFACE MATERIAL FOR DISPLAY, TOUCH PANEL MEMBER, LIQUID CRYSTAL DISPLAY DEVICE, AND ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE 大日本印刷株式会社 2019-04-25 WO disclosed
US-20190092913-A1 POLYIMIDE FILM, METHOD FOR PRODUCING POLYIMIDE FILM, AND POLYIMIDE PRECURSOR RESIN COMPOSITION DAI NIPPON PRINTING CO., LTD. (JP) 2019-03-28 US disclosed
US-8993710-B1 Polyimides derived from novel asymmetric benzophenone dianhydrides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2015-03-31 US disclosed
US-8093348-B1 Polyimides derived from novel asymmetric dianhydrides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2012-01-10 US disclosed
US-8093348-B1 Polyimides derived from novel asymmetric dianhydrides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2012-01-10 US disclosed
US-8093348-B1 Polyimides derived from novel asymmetric dianhydrides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2012-01-10 US disclosed
US-8093348-B1 Polyimides derived from novel asymmetric dianhydrides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2012-01-10 US disclosed
US-7381849-B1 Synthesis of asymmetric tetracarboxylic acids and dianhydrides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2008-06-03 US disclosed
US-7381849-B1 Synthesis of asymmetric tetracarboxylic acids and dianhydrides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2008-06-03 US disclosed
US-7381849-B1 Synthesis of asymmetric tetracarboxylic acids and dianhydrides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2008-06-03 US disclosed
US-7381849-B1 Synthesis of asymmetric tetracarboxylic acids and dianhydrides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2008-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10059682-B1 Asymmetric dianhyrdrides and methods of making the same BTD, AASDHPPT, ACMSD ALOX15 1543/4885TDP1 3085/4885ALDH1A1 689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.