SCHEMBL544762

SCHEMBL544762

O=C1OC(=O)c2c1cccc2C(c1cccc2c1C(=O)OC2=O)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TYMS P04818 4/20 0.39
CES1 P23141 1/20 0.35
NOTUM Q6P988 3/20 0.32
PSMB8 P28062 1/20 0.32
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11729711 0.85 ALOX15 (0.44) ALOX15TDP1TYMSCES1NOTUM
SCHEMBL308616 0.85 ALOX15 (0.36) ALOX15TDP1TYMS
SCHEMBL11887459 0.82 ALOX15 (0.39) ALOX15TDP1TYMSCES1NOTUM
SCHEMBL8597036 0.82 ALOX15 (0.39) ALOX15TDP1TYMSCES1NOTUM
SCHEMBL443593 0.80 ALOX15 (0.36) ALOX15TDP1TYMSCES1
SCHEMBL28252490 0.80 ALOX15 (0.36) ALOX15TDP1TYMSCES1
SCHEMBL12475740 0.78 TDP1 (0.39) ALOX15TDP1TYMSCES1NOTUM
SCHEMBL434702 0.77 ALOX15 (0.44) ALOX15TDP1TYMSCES1NOTUM
SCHEMBL7074292 0.77 TDP1 (0.44) ALOX15TDP1TYMS
SCHEMBL11726146 0.77 ALOX15 (0.44) ALOX15TDP1TYMSCES1NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 438 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11566108-B2 Polyimide film, laminate and surface material for display DAI NIPPON PRINTING CO., LTD. (JP) 2023-01-31 US claimed
CN-115505151-A Low-dielectric-constant super-crosslinked polymer/polyimide composite film used under high frequency, preparation method and application 浙江理工大学 2022-12-23 CN claimed
CN-114702706-B 400 ℃ high-temperature-resistant colorless transparent polyimide film and preparation method thereof 哈尔滨工业大学 2022-11-08 CN claimed
CN-114702706-A 400 ℃ high-temperature-resistant colorless transparent polyimide film and preparation method thereof 哈尔滨工业大学 2022-07-05 CN claimed
CN-112679954-A Low-dielectric-constant polyimide film and preparation method thereof 安徽省长荣新材料科技有限公司 2021-04-20 CN claimed
EP-3720903-A1 THERMALLY TREATED POLYAMIC AMIDE AEROGEL Blueshift Materials, Inc. (US) 2020-10-14 EP claimed
EP-3703847-A1 CARBON MOLECULAR SIEVE MEMBRANES CONTAINING A GROUP 13 METAL AND METHOD TO MAKE THEM Dow Global Technologies LLC (US) 2020-09-09 EP claimed
US-20200276542-A1 CARBON MOLECULAR SIEVE MEMBRANES CONTAINING A GROUP 13 METAL AND METHOD TO MAKE THEM DOW GLOBAL TECHNOLOGIES LLC (US) 2020-09-03 US claimed
CN-111225736-A Group 13 metal-containing carbon molecular sieve membrane and method for producing same 陶氏环球技术有限责任公司 2020-06-02 CN claimed
WO-2019112855-A1 THERMALLY TREATED POLYAMIC AMIDE AEROGEL Blueshift Materials, Inc. (US) 2019-06-13 WO claimed
WO-2008021063-A1 POLYMER MEMBRANE FOR SEPERATING AROMATIC AND ALIPHATIC COMPOUNDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-02-21 WO claimed
US-20070117990-A1 Method of purifying dianhydrides GENERAL ELECTRIC COMPANY (US) 2007-05-24 US claimed
US-20060293421-A1 Methods for embossing and embossed articles formed thereby CITIBANK, N.A., AS COLLATERAL AGENT 2006-12-28 US claimed
US-20060135791-A1 Method of purifying dianhydrides GENERAL ELECTRIC COMPANY 2006-06-22 US claimed
US-6977057-B2 Embossing process GENERAL ELECTRIC (US) 2005-12-20 US claimed
US-20030057601-A1 Embossing a surface comprising a polymer and a plasticizer having reactive moieties and reacting the reactive moieties to increase the glass transition temperature of the embossed polymer surface CITIBANK, N.A., AS COLLATERAL AGENT 2003-03-27 US claimed
US-5922167-A MOUNTING A CHIP ON A LEAD FRAME WITHOUT ADVERSELY AFFECTING SOLDERING OF THE LEADS OF THE CHIP BY PRESSING IN PLACE AND HEATING A PASTE OF POLYIMIDE BASED ON AROMATIC TETRAACIDS AND DIAMINES AND ALIPHATIC DIAMINES; SILOXANE-FREE OCCIDENTIAL CHEMICAL CORPORATION (US) 1999-07-13 US claimed
US-5688848-A PLASTICIZER WITH POLYIMIDES GENERAL ELECTRIC COMPANY (US) 1997-11-18 US claimed
US-5430218-A Dehydrogenation using dehydrogenation catalyst and polymer-porous solid composite membrane CHEVRON U.S.A. INC. (US) 1995-07-04 US claimed
US-5395917-A Polyester or polyamide copolymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-03-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070117990-A1 Method of purifying dianhydrides CA7, HDHD5, CA2 ALOX15 4790/4885TDP1 1591/4885TYMS 3734/4885
US-20060135791-A1 Method of purifying dianhydrides SAMHD1, TREH, DOHH ALOX15 4090/4885TDP1 2169/4885TYMS 1308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.