Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 7/20 | 0.46 |
| ▸ | GSK3B | P49841 | 7/20 | 0.46 |
| ▸ | SRPK1 | Q96SB4 | 5/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | PRKX | P51817 | 1/20 | 0.46 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.46 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 2/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 11/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 10/20 | 0.43 |
| ▸ | HIPK4 | Q8NE63 | 5/20 | 0.43 |
| ▸ | STK3 | Q13188 | 5/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.43 |
| ▸ | CDK8 | P49336 | 5/20 | 0.43 |
| ▸ | CDK2 | P24941 | 4/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.43 |
| ▸ | FLT3 | P36888 | 3/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.43 |
| ▸ | PBK | Q96KB5 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9891927 | 0.82 | GSK3A (0.52) | GSK3AGSK3BSRPK1AURKAPRKX | |
| SCHEMBL13170010 | 0.80 | KDM4E (0.56) | GSK3AGSK3BSRPK1AURKAPRKX | |
| SCHEMBL13645654 | 0.74 | POLB (0.58) | — | |
| SCHEMBL2635287 | 0.73 | TAS2R14 (0.57) | GSK3AGSK3BSRPK1AURKAPRKX | |
| SCHEMBL29676316 | 0.72 | ACACB (0.53) | ACACBTAS2R14 | |
| SCHEMBL1464329 | 0.72 | CLK4 (0.45) | GSK3AGSK3BSRPK1AURKAPRKX | |
| SCHEMBL5031654 | 0.71 | P2RX7 (0.53) | GSK3AGSK3BSRPK1AURKAPRKX | |
| SCHEMBL29640129 | 0.71 | P2RX7 (0.53) | GSK3AGSK3BSRPK1AURKAPRKX | |
| SCHEMBL1464316 | 0.71 | GSK3A (0.49) | GSK3AGSK3BSRPK1AURKAPRKX | |
| SCHEMBL18425134 | 0.71 | ACVR1 (0.49) | GSK3AGSK3BSRPK1AURKAPRKX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658864-A | Preparation method of key intermediate of sabatier | 新天地医药技术研究院(郑州)有限公司 | 2024-03-08 | — | — | CN | disclosed |