Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9899981 | 0.80 | MEN1 (0.51) | CYP2C19MEN1KMT2ANPC1RAB9A | |
| SCHEMBL30863581 | 0.78 | UCHL1 (0.40) | CNR1CNR2CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL26008895 | 0.75 | CNR1 (0.40) | CNR1CNR2CYP2C19MEN1KMT2A | |
| SCHEMBL31437460 | 0.74 | GSK3B (0.41) | CNR1CNR2ALDH1A1MAOAMAOB | |
| SCHEMBL15081325 | 0.74 | MAOA (0.37) | CNR1CNR2MAOAMAOBGSK3B | |
| SCHEMBL31437508 | 0.73 | RORC (0.38) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24896677 | 0.72 | L3MBTL1 (0.46) | CNR1CNR2MEN1KMT2AALDH1A1 | |
| SCHEMBL27797896 | 0.72 | HDAC3 (0.52) | GSK3BHDAC3HDAC8NCOR2 | |
| SCHEMBL31017347 | 0.71 | MAPK1 (0.38) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL30895142 | 0.71 | MAPK1 (0.38) | MEN1KMT2AALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125389-A1 | MEMBRANE-ASSOCIATED TYROSINE AND THREONINE KINASE INHIBITOR AND USE THEREOF | HAINAN SIMCERE ZAIMING PHARMACEUTICAL CO LTD (CN) | 2026-05-07 | — | — | US | disclosed |
| CN-119894902-A | Membrane associated tyrosine and threonine kinase inhibitors and uses thereof | 海南先声再明医药股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024061343-A1 | MEMBRANE-ASSOCIATED TYROSINE AND THREONINE KINASE INHIBITOR AND USE THEREOF | 先声再明医药有限公司 | 2024-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125389-A1 | MEMBRANE-ASSOCIATED TYROSINE AND THREONINE KINASE INHIBITOR AND USE THEREOF | PKMYT1, PKN1, ROS1 | CNR1 1943/4885CNR2 2690/4885CYP2C19 4006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.