Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6347304 | 0.84 | MMP2 (0.53) | CTSSCTSKS1PR3MMP2MMP9 | |
| SCHEMBL27770063 | 0.84 | MMP2 (0.53) | CTSSCTSKS1PR3MMP2MMP9 | |
| SCHEMBL16789062 | 0.83 | CTSS (0.49) | CTSSCTSKMMP2MMP9ANPEP | |
| SCHEMBL8512117 | 0.81 | CYP2D6 (0.54) | CTSSCTSKS1PR3ATMSCN9A | |
| SCHEMBL8512111 | 0.81 | CYP2D6 (0.54) | CTSSCTSKS1PR3ATMSCN9A | |
| SCHEMBL8516088 | 0.81 | CYP2D6 (0.54) | CTSSCTSKS1PR3ATMSCN9A | |
| SCHEMBL16789073 | 0.81 | CYP2D6 (0.54) | CTSSCTSKS1PR3ATMSCN9A | |
| SCHEMBL16789065 | 0.81 | CTSK (0.51) | CTSSCTSKS1PR3MMP2MMP9 | |
| SCHEMBL8512023 | 0.80 | LMNA (0.60) | CTSSCTSKMAPT | |
| SCHEMBL8512028 | 0.80 | LMNA (0.60) | CTSSCTSKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117677620-A | Antiviral prodrugs of Entecavir (ETV) and formulations thereof | 斯克里普斯研究学院 | 2024-03-08 | — | — | CN | disclosed |