Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Trichloroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.91 |
| ▸ | TP53 | P04637 | 1/20 | 0.91 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trichloroacetic Acid SCHEMBL1062069 | 1.00 | — | — | |
| Trichloroacetic Acid SCHEMBL27171216 | 0.96 | — | — | |
| Trichloroacetic Acid SCHEMBL27171214 | 0.96 | — | — | |
| Trichloroacetic Acid SCHEMBL3220 | 0.95 | — | — | |
| Trichloroacetic Acid SCHEMBL10493657 | 0.95 | TSHR (1.00) | TSHRALDH1A1TP53CYP1A2CA1 | |
| Trichloroacetic Acid SCHEMBL1331160 | 0.95 | — | — | |
| Trichloroacetic Acid SCHEMBL10745837 | 0.95 | — | — | |
| Trichloroacetic Acid SCHEMBL38661501 | 0.95 | — | — | |
| Trichloroacetic Acid SCHEMBL1331955 | 0.95 | — | — | |
| Trichloroacetic Acid SCHEMBL5311061 | 0.95 | TSHR (1.00) | TSHRALDH1A1TP53CYP1A2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119972062-A | Preparation and application of nano-catalyst for interfering metabolism of colorectal cancer formic acid | 中国人民解放军海军军医大学第一附属医院 | 2025-05-13 | — | — | CN | claimed |
| CN-114486767-B | Au/TiO2PEDOT sensitive film material, preparation method thereof and application thereof in sensor | 天津理工大学 | 2025-04-11 | — | — | CN | claimed |
| CN-120195138-A | Method for quantitatively detecting bilirubin based on assembly of double-emission gold nanoclusters and polyacrylamide hydrochloride | 桂林电子科技大学 | 2025-06-24 | — | — | CN | disclosed |
| CN-120054526-A | Oxygen-defect type titanium dioxide-loaded gold-copper alloy photocatalyst and preparation method and application thereof | 清华大学 | 2025-05-30 | — | — | CN | disclosed |
| CN-114486767-B | Au/TiO2PEDOT sensitive film material, preparation method thereof and application thereof in sensor | 天津理工大学 | 2025-04-11 | — | — | CN | disclosed |
| CN-118652324-B | Application of monoclonal antibody specifically binding to CD2v protein of ASFV in ASF diagnosis and identification of ASFV virulent strain and CD2v gene deletion attenuated strain | 河北农业大学 | 2025-01-21 | — | — | CN | disclosed |
| CN-118425260-A | Sensor and manufacturing method thereof | 山东云海国创云计算装备产业创新中心有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-118329863-A | Tumor metastasis early diagnosis reagent based on polypeptide functionalized plasma gold nanostar | 南京工业大学 | 2024-07-12 | — | — | CN | disclosed |
| CN-110526198-B | Flexible pressure sensor based on hemispherical microstructure and manufacturing method thereof | 深圳先进技术研究院 | 2024-05-28 | — | — | CN | disclosed |
| CN-117783097-A | Method and kit for rapidly detecting chromium ions | 上海师范大学 | 2024-03-29 | — | — | CN | disclosed |