Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115604 | 0.82 | ALDH1A1 (0.51) | LMNAPOLBMAPK1MEN1KMT2A | |
| SCHEMBL8616595 | 0.81 | LMNA (0.46) | GSTO1LMNAPOLBMAPK1CASP3 | |
| SCHEMBL8118567 | 0.80 | MEN1 (0.50) | LMNAPOLBMAPK1MEN1KMT2A | |
| SCHEMBL30833308 | 0.76 | CYP3A4 (0.71) | GSTO1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL4003878 | 0.76 | CYP3A4 (0.71) | GSTO1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL2133754 | 0.76 | BCHE (0.61) | LMNAMAPK1CASP3MEN1KMT2A | |
| SCHEMBL10375232 | 0.75 | ALDH1A1 (0.47) | MAPK1MEN1KMT2AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL21296615 | 0.74 | BCHE (0.59) | LMNAMAPK1CASP3MEN1KMT2A | |
| SCHEMBL7751082 | 0.73 | GSTO1 (0.56) | GSTO1LMNACASP3NPC1MITF | |
| SCHEMBL4002460 | 0.72 | TSHR (0.73) | LMNAMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |