Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13050473 | 0.84 | PDE10A (0.39) | AHRALDH1A1PDE10AKDM4ESMN1; SMN2 | |
| SCHEMBL1243656 | 0.80 | ALDH1A1 (0.45) | AHRALDH1A1PDE10AKDM4ESMN1; SMN2 | |
| SCHEMBL17232815 | 0.80 | DYRK1A (0.49) | AHRALDH1A1PDE10AKDM4ESMN1; SMN2 | |
| SCHEMBL756100 | 0.78 | KDM4E (0.50) | AHRALDH1A1PDE10AKDM4ESMN1; SMN2 | |
| SCHEMBL17234784 | 0.76 | PDE10A (0.40) | AHRPDE10AKDM4EDRD2DRD4 | |
| SCHEMBL22958080 | 0.76 | AHR (0.35) | AHRALDH1A1PDE10AKDM4ESMN1; SMN2 | |
| SCHEMBL17229829 | 0.76 | MCHR1 (0.38) | AHRPDE10AKDM4EPTGS1PTGS2 | |
| SCHEMBL21033315 | 0.75 | PTGS1 (0.41) | AHRALDH1A1PDE10AKDM4EPTGS1 | |
| SCHEMBL30845789 | 0.74 | TGFBR1 (0.43) | ALDH1A1KDM4E | |
| SCHEMBL3086869 | 0.73 | KDM4E (0.44) | AHRALDH1A1PDE10AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930331-B1 | METHOD FOR PRODUCING IMIDAZO[1,2-b]PYRIDAZINE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2013-03-13 | — | — | EP | disclosed |
| US-8334379-B2 | Process for producing imidazo[1,2-b]pyridazine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-18 | — | — | US | disclosed |
| US-20100234597-A1 | PROCESS FOR PRODUCING IMIDAZO[1,2-b]PYRIDAZINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-1930331-A1 | METHOD FOR PRODUCING IMIDAZO[1,2-b]PYRIDAZINE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234597-A1 | PROCESS FOR PRODUCING IMIDAZO[1,2-b]PYRIDAZINE COMPOUND | CYP1B1, CYP4Z1, CYP2J2 | AHR 715/4885ALDH1A1 409/4885PDE10A 2514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.