SCHEMBL30869402

SCHEMBL30869402

CN1C[C@H]2C[C@@H]1CN2CCN1c2ccc(-c3cnc4[nH]ncc4c3)cc2Oc2cc(-c3cnc4[nH]ncc4c3)ccc21

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 15/20 0.47
KCNH2 Q12809 12/20 0.46
TNIK Q9UKE5 2/20 0.37
PIK3C3 Q8NEB9 2/20 0.35
PDE10A Q9Y233 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869672 0.89 CHRNA7 (0.56) CHRNA7KCNH2
SCHEMBL30869646 0.89 CHRNA7 (0.56) CHRNA7KCNH2
SCHEMBL30869658 0.87 CHRNA7 (0.47) CHRNA7KCNH2TNIKPIK3C3
SCHEMBL30869429 0.87 CHRNA7 (0.55) CHRNA7KCNH2TNIK
SCHEMBL30869683 0.86 GSK3B (0.42) CHRNA7KCNH2TNIKPIK3C3PDE10A
SCHEMBL30869436 0.85 TNIK (0.36) CHRNA7KCNH2TNIKPIK3C3PDE10A
SCHEMBL30869447 0.83 CHRNA7 (0.57) CHRNA7KCNH2TNIK
SCHEMBL30869491 0.83 CHRNA7 (0.57) CHRNA7KCNH2TNIK
SCHEMBL30869548 0.79 BRAF (0.42) CHRNA7KCNH2
SCHEMBL30869473 0.78 CHRNA7 (0.49) CHRNA7KCNH2TNIK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 CHRNA7 1850/4885KCNH2 851/4885TNIK 3440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.