SCHEMBL30869658

SCHEMBL30869658

CN1C[C@H]2C[C@@H]1CN2CCN1c2ccc(-c3cnc4[nH]ncc4c3)cc2Sc2cc(-c3cnc4[nH]ncc4c3)ccc21

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 16/20 0.47
KCNH2 Q12809 13/20 0.46
ABL1 P00519 1/20 0.36
TNIK Q9UKE5 1/20 0.35
PIK3C3 Q8NEB9 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869402 0.87 CHRNA7 (0.47) CHRNA7KCNH2TNIKPIK3C3
SCHEMBL30869797 0.84 FGFR1 (0.39) CHRNA7KCNH2ABL1PIK3C3
SCHEMBL30869668 0.83 NUDT1 (0.39) CHRNA7KCNH2
SCHEMBL30869706 0.78 CHRNA7 (0.38) CHRNA7KCNH2ABL1
SCHEMBL30869697 0.78 BRAF (0.42) CHRNA7KCNH2ABL1
SCHEMBL30869758 0.77 KDM1A (0.47) TNIKPIK3C3
SCHEMBL30869646 0.75 CHRNA7 (0.56) CHRNA7KCNH2
SCHEMBL30869672 0.75 CHRNA7 (0.56) CHRNA7KCNH2
SCHEMBL30869447 0.74 CHRNA7 (0.57) CHRNA7KCNH2TNIK
SCHEMBL30869491 0.74 CHRNA7 (0.57) CHRNA7KCNH2TNIK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed