SCHEMBL30869448

SCHEMBL30869448

CC(C)(C)OC(=O)N1C[C@H]2C[C@@H]1CN2CCN1c2ccc(Br)cc2Oc2cc(Br)ccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.40
KCNK3 O14649 3/20 0.39
KCNK9 Q9NPC2 3/20 0.39
FGFR1 P11362 1/20 0.38
FGFR2 P21802 1/20 0.38
FGFR4 P22455 1/20 0.38
FGFR3 P22607 1/20 0.38
KDR P35968 1/20 0.38
F13A1 P00488 1/20 0.36
TGM2 P21980 1/20 0.36
TGM1 P22735 1/20 0.36
GPR119 Q8TDV5 1/20 0.36
SPR P35270 1/20 0.35
PARP1 P09874 1/20 0.35
USP30 Q70CQ3 2/20 0.34
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
HDAC1 Q13547 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869499 0.90 FGFR1 (0.39) HSD11B1KCNK3KCNK9FGFR1FGFR2
SCHEMBL30869634 0.90 FGFR1 (0.39) HSD11B1KCNK3KCNK9FGFR1FGFR2
SCHEMBL30869425 0.90 FGFR1 (0.39) HSD11B1KCNK3KCNK9FGFR1FGFR2
SCHEMBL30869536 0.86 HSD11B1 (0.40) HSD11B1KCNK3KCNK9FGFR1FGFR2
SCHEMBL30869490 0.81 PIK3CD (0.42) HSD11B1KCNK3KCNK9FGFR1FGFR2
SCHEMBL30869457 0.81 PIK3CD (0.42) HSD11B1KCNK3KCNK9FGFR1FGFR2
SCHEMBL30869785 0.79 FGFR1 (0.36) HSD11B1KCNK3KCNK9FGFR1FGFR2
SCHEMBL30869913 0.79 FGFR1 (0.36) HSD11B1KCNK3KCNK9FGFR1FGFR2
SCHEMBL30869789 0.79 FGFR1 (0.36) HSD11B1KCNK3KCNK9FGFR1FGFR2
SCHEMBL19869927 0.73 HSD11B1 (0.42) HSD11B1KCNK3KCNK9FGFR1FGFR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 HSD11B1 2981/4885KCNK3 1656/4885KCNK9 1810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.