SCHEMBL30869490

SCHEMBL30869490

CC(C)(C)OC(=O)N1C[C@H]2C[C@@H]1CN2CCN1c2ccc(-c3ccc4[nH]ncc4c3)cc2Oc2cc(-c3ccc4[nH]ncc4c3)ccc21

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 2/20 0.42
CHRNA7 P36544 4/20 0.40
KCNH2 Q12809 1/20 0.40
PARP1 P09874 1/20 0.39
FGFR1 P11362 1/20 0.38
FGFR2 P21802 1/20 0.38
FGFR4 P22455 1/20 0.38
FGFR3 P22607 1/20 0.38
KDR P35968 1/20 0.38
KCNK3 O14649 4/20 0.36
KCNK9 Q9NPC2 4/20 0.36
ROCK2 O75116 3/20 0.34
ROCK1 Q13464 2/20 0.34
SPR P35270 1/20 0.34
HSD11B1 P28845 1/20 0.34
ABL1 P00519 1/20 0.34
GPR119 Q8TDV5 1/20 0.34
RET P07949 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869457 1.00 PIK3CD (0.42) PIK3CDCHRNA7KCNH2PARP1FGFR1
SCHEMBL30869591 0.94 PIK3CD (0.41) PIK3CDCHRNA7KCNH2PARP1FGFR1
SCHEMBL30869607 0.94 PIK3CD (0.41) PIK3CDCHRNA7KCNH2PARP1FGFR1
SCHEMBL30869666 0.94 PIK3CD (0.41) PIK3CDCHRNA7KCNH2PARP1FGFR1
SCHEMBL30869774 0.87 PARP1 (0.38) PARP1FGFR1FGFR2FGFR4FGFR3
SCHEMBL30869691 0.86 PIK3CD (0.39) PIK3CDCHRNA7KCNH2PARP1FGFR1
SCHEMBL30869471 0.86 PIK3CD (0.39) PIK3CDCHRNA7KCNH2PARP1FGFR1
SCHEMBL30869646 0.84 CHRNA7 (0.56) CHRNA7KCNH2FGFR1KDRROCK2
SCHEMBL30869672 0.84 CHRNA7 (0.56) CHRNA7KCNH2FGFR1KDRROCK2
SCHEMBL30869448 0.81 HSD11B1 (0.40) PARP1FGFR1FGFR2FGFR4FGFR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 PIK3CD 127/4885CHRNA7 1850/4885KCNH2 851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.