SCHEMBL30869554

SCHEMBL30869554

O=S1(=O)NCc2cc(Br)ccc2N1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA12 O43570 1/20 0.40
CA4 P22748 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CMA1 P23946 1/20 0.40
AHR P35869 1/20 0.40
BRD4 O60885 1/20 0.39
PNMT P11086 6/20 0.37
ASIC3 Q9UHC3 1/20 0.37
ADRA2A P08913 3/20 0.36
ADRA2B P18089 2/20 0.36
ADRA2C P18825 2/20 0.36
SLC40A1 Q9NP59 1/20 0.35
TDP2 O95551 1/20 0.34
PARP10 Q53GL7 1/20 0.34
PARP11 Q9NR21 1/20 0.34
TGM2 P21980 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30364567 0.79 AHR (0.43) CA1CA2CA12CA4CA7
SCHEMBL31568203 0.77 CA2 (0.47) CA1CA2CA12CA4CA7
SCHEMBL7901542 0.75 PARP1 (0.35) SLC40A1
SCHEMBL15661473 0.74 CA2 (0.42) CA1CA2CA12CA4CA7
SCHEMBL36942249 0.74 CA2 (0.42) CA1CA2CA12CA4CA7
SCHEMBL2254955 0.73 PDE7A (0.42) CA1CA2CA12CA4CA7
SCHEMBL4595932 0.71 CA2 (0.40) CA1CA2CA12CA4CA7
SCHEMBL12077853 0.70 CA1 (0.50) CA1CA2CA12CA4CA7
SCHEMBL31387209 0.70 CA1 (0.50) CA1CA2CA12CA4CA7
SCHEMBL4596034 0.70 KIF11 (0.52) CA12CA9ASIC3TDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 CA1 3576/4885CA2 554/4885CA12 4766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.